In this article, we discuss the ethical dimensions for the prescribing behaviours of opioids for a chronic pain patient, a scenario commonly witnessed by many physicians. The opioid epidemic in the USA and Canada is well known, existing since the late 1990s, and individuals are suffering and dying as a result of the easy availability of prescription opioids. More recently, this problem has been seen outside of North America affecting individuals at similar rates in Australia and Europe. We argue that (...) physicians are also confronted with an ethical crisis where a capitalist-consumerist society is contributing to this opioid crisis in which societal, legal and business interests push physicians to overprescribe opioids. Individual physicians often find themselves unequipped and unsupported in attempts to curb the prescribing of opioid medications and balance competing goals of alleviating pain against the judicious use of pain medications. Physicians, individually and as a community, must reclaim the ethical mantle of our profession, through a more nuanced understanding of autonomy and beneficence. Furthermore, physicians and the medical community at large have a fiduciary duty to patients and society to play a more active role in curbing the widespread distribution of opioids in our communities. (shrink)

Jones & Love (J&L) suggest that Bayesian approaches to the explanation of human behavior should be constrained by mechanistic theories. We argue that their proposal misconstrues the relation between process models, such as the Bayesian model, and mechanisms. While mechanistic theories can answer specific issues that arise from the study of processes, one cannot expect them to provide constraints in general.

This study described parent participation in the informed consent conference for randomized clinical trials (RCTs) in childhood leukemia and documented the relationship of physician communication to parent participation. Parents of 140 children with newly diagnosed leukemia who were eligible for RCTs were studied at six sites using comprehensive methods involving direct observation and transcripts of parent-physician communication based on audiotapes. Parent participation during the informed consent conference reflected a wide range of content categories. Consistent with hypotheses, Physician Rapport and Partnership (...) Building related to parent participation in the informed consent conference but Information Giving did not. Higher parent socioeconomic status also was related to greater parent participation for two of three measures of parent participation. Findings suggest that physician behaviors that provide support and facilitate communication may enhance parental participation in the informed consent conference for RCTs in childhood leukemia. (shrink)

An outline of the material covered in courses on Formal and Informal Logic. The outline includes chapters on mathematical approaches to logic as well as on fallacies, deduction and induction, probability, and other major topics. Logic is traditionally taught by means of problem solving exercises, so the subject is well suited to a Schaum's Outline approach.

Gene therapy approaches have great promise in the treatment of neurodegenerative disorders and malignant brain tumors. Neuwelt et al. review available viral-mediated gene therapy methods and their blood-brain-barrier (BBB) disruption delivery technique, briefly mentioning nonviral mediated gene therapy methods. This commentary discussed the BBB disruption delivery technique, viral and nonviral mediated gene therapy approaches to Parkinson's disease, and the potential use of antisense oligo to suppress malignant brain tumors.

We describe how the set of tools, practices, and social relations known as “precision agriculture” is defined, promoted, and debated. To do so, we perform a critical discourse analysis of popular and trade press websites. Promoters of precision agriculture champion how big data analytics, automated equipment, and decision-support software will optimize yields in the face of narrow margins and public concern about farming’s environmental impacts. At its core, however, the idea of farmers leveraging digital infrastructure in their operations is not (...) new, as agronomic research in this vein has existed for over 30 years. Contemporary discourse in precision ag tends to favour emerging digital technologies themselves over their embeddedness in longstanding precision management approaches. Following several strands of science and technology studies research, we explore what rhetorical emphasis on technical innovation achieves, and argue that this discourse of novelty is a reinvention of precision agriculture in the context of the growing “smart” agricultural economy. We overview six tensions that remain unresolved in this promotional rhetoric, concerning the definitions, history, goals, adoption, uses, and impacts of precision agriculture. We then synthesize these in a discussion of the extent to which digital tools are believed to displace farmer decision-making and whether digital agriculture addresses the biophysical heterogeneity of farm landscapes or land itself has become an “experimental technology”—a way to advance the general development of artificial intelligence. This discussion ultimately helps us name a larger dilemma: that the smart agricultural economy is perhaps less about supporting land and its stewards than promising future tech and profits. (shrink)

This narrative review summarizes the empirical literature on children's competence for consent and assent in research and treatment settings. Studies varied widely regarding methodology, particularly in the areas of participant sampling, situational context studied (e.g., psychological versus medical settings), procedures used (e.g., lab-based vs. real-world approaches), and measurement of competence. This review also identified several fundamental dilemmas underlying approaches to children's informed consent. These dilemmas, including autonomy versus best interests approaches, legal versus psychological or ethical approaches, child- versus family-based approaches, (...) and approaches that emphasize consent versus those that emphasize assent, have implications for the measurement of children's competence and interpretation of findings. Recommendations for future research in the area of children's informed consent include the use of diverse samples and control groups, development of multidimensional and standardized measures of competence, utilization of observational methods and longitudinal designs, examination of noncognitive aspects of children's competence, and comparison of children's competence for treatment and research decisions. (shrink)

Tests of economic theory often focus on choice outcomes and find significant individual differences in these outcomes. This variability may mask universal psychological processes that lead to different choices because of differences across cultures in the information people have available when making decisions. On this view, decision making research within and across cultures must focus on the processes underlying choice.

In the year 1471 a member of the Sorbonne, Guillaume Fichet, looking back on the history of what today we should call communication technology, divided it into three periods: antiquity , a subsequent period which we should identify as the Middle Ages , and a period just beginning . Just over five hundred years later an American scholar, Walter J. Ong, looking back on a longer historical span, divided it into orality, writing, printing, and electronic communications. No matter how much (...) these two figures may differ over details, they occupy a similar position: each stands at the start of a communications shift which has alerted him to changes in the past, and Ong claims explicitly that contrasts “between electronic media and print have sensitized us to the earlier contrast between writing and orality.” We do not have to go as far as Eric A. Havelock, who suggests that our new awareness can be precisely dated by a number of publications appearing in the annus mirabilis 1963 , in order to accept the general point that recent work has been stimulated by recent technology. (shrink)

Written by one of the instrumental figures in environmental ethics, Nature as Subject traces the development of an ethical policy that is centered not on human beings, but on itself. Katz applies this idea to contemporary environmental problems, introducing themes of justice, domination, imperialism, and the Holocaust. This volume will stand as a foundational work for environmental scholars, government and industry policy makers, activists, and students in advanced philosophy and environmental studies courses.

This book considers how observations about the past influence future behaviour, as expressed in language. Focusing on information gathered from speech and other evidence sources, the author offers a model of how judgements about reliability can be made, and how such judgements factor into how people treat information they acquire via those sources.

Written in debate format, this book covers developing fields such as social cognition, as well as classic areas such as memory, learning, perception and categorization. The links between emotion and memory, learning, perception, categorization, social judgements, and behavior are addressed.

This book examines the logical foundations of visual information: information presented in the form of diagrams, graphs, charts, tables, and maps. The importance of visual information is clear from its frequent presence in everyday reasoning and communication, and also in compution. Chapters of the book develop the logics of familiar systems of diagrams such as Venn diagrams and Euler circles. Other chapters develop the logic of higraphs, Pierce diagrams, and a system having both diagrams and sentences among its well-formed representations. (...) Syntax, semantics, rules of inference and soundness and completeness results are provided for each of the systems. In addition to developing the logic of diagrams, key questions about the status of visual information Hammer discusses, such as the relationship between the language and visually-presented information. (shrink)

Michael Tomasello ( 2016 ) prominently defends the view that there are uniquely human capacities required for shared intentions, therefore great apes do not share intentions. I show that these uniquely human capacities for abstraction are not necessary for shared intentionality. Excluding great apes from shared intentions because they lack certain capacities for abstraction assumes a specific interpretation of shared intentionality, which I call the Roleplaying Model. I undermine the necessity of abstraction for shared intentionality by presenting an alternative model (...) of shared intentionality, which I call the Normative Model. It is a modification of Margaret Gilbert’s ( 2013 ) Plural Subject theory, which I modify such that it is, in principle, compatible with nonhuman shared intentionality. To do this, I substitute Gilbert’s account of obligation for Kristin Andrews’ ( 2020 ) account of animal social norms. In this Normative Model, uniquely human capacities for abstraction are not required for shared intentionality. By undermining the necessity of uniquely human abstraction, I make cases of prima-facie cooperation in chimpanzees plausible instances of shared intentionality. The Roleplaying Model’s denial of nonhuman shared intentionality creates a problem insofar as apparent shared intentional activity cannot be fully analyzed. The Normative Model resolves this problem. (shrink)

A critique of Rorty's own provocative political philosophy, as well as an in-depth look at both the issues concerning the relationship between the public and the private, and arguments on the role of reason in liberal political discourse generally.

In The Human Animal I argued that we are animals, and that those animals do not persist by virtue of any sort of psychological continuity. Rather, personal identity in this sense consists in having the same biological life. And I said that a human life requires a functioning brainstem. Rina Tzinman takes this and other remarks to imply that personal identity consists in the continued functioning of the brainstem, which looks clearly false. I say it doesn’t follow. But Alan Shewmon (...) appears to have refuted my claim about the brainstem. (shrink)

There is a lack of research explicitly demonstrating the potential of applying critical realism in qualitative empirical Management and Organization Studies. If scholars are to obtain the exp...

Accounts of personal identity over time are supposed to fall into two broad categories: 'complex views' saying that our persistence consists in something else, and 'simple views' saying that it doesn' t. But it is impossible to characterize this distinction in any satisfactory way. The debate has been systematically misdescribed. After arguing for this claim, the paper says something about how the debate might be better characterized.

Modern scholarship has drawn hasty and numerous parallels between the Yellow Peril discourses of the 19th- and 20th-century plagues and the recent racialization of infectious disease in the 21st-century. While highlighting these similarities is politically useful against Sinophobic epidemic narratives, Michel Foucault argues that truly understanding the past’s continuity in the present requires a more rigorous genealogical approach. Employing this premise in a comparative analysis, this work demonstrates a critical discontinuity in the epidemic imaginary that framed the Chinese as pathogenic. (...) Consequently, those seeking to prevent future disease racialization must understand modern Sinophobia as fundamentally distinct from that of the past. (shrink)

Canada’s Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans mandates that all research involving human subjects be reviewed and approved by a research ethics board . We have little evidence on how researchers are dealing with this requirement in multisite studies, which involve more than one REB. We retrospectively examined 22 REB submissions for two minimal-risk, multisite studies in leading Canadian institutions. Most REBs granted expedited review to the studies, while one declared the application to be exempt from review. (...) Time between submission and approval ranged greatly, from four to 546 days. We received a total of 155 REB queries for changes and clarifications, most of which asked for further information, clarification, or additional documents. Less than a third of the REB queries were requests for specific changes, and a vast majority had a very limited impact on the research projects. Institutions also varied broadly in their description of what was required of local principal investigators. We conclude that the organizational and practical challenges these results imply could deter researchers from embarking on multisite research projects, and that recently proposed changes to the TCPS will not solve these problems. (shrink)

Classical logic is traditionally introduced by itself, but that makes it seem arbitrary and unnatural. This text introduces classical alongside several nonclassical logics (relevant, constructive, quantative, paraconsistent).

Points-based grading, though now traditional, faces powerful critiques: Such grading creates a low road to passing, it undermines motivation, it wastes time, and it causes stress. It creates an illusion of mathematical precision. It is unfriendly to necessary conditions for satisfactory performance. This paper defends the alternative of specifications grading. Specifications grading grades only on whether work meets a set of expectations for satisfactory performance, with the expectations set at a high but reachable level. With a high bar also comes (...) opportunities to revise unsatisfactory work. I summarize arguments from the literature in support of the system, but I also give account of my two-year experiment in philosophy courses with specifications grading. Compared with points-based grading, specifications grading appears to motivate students better and helps them learn more. I consider objections from both traditionalists and so-called ‘ungraders.’ The former hope to secure the benefits of specifications grading while still keeping points. The latter favor eliminating grading altogether. (shrink)

The paper concerns the metaphysical possibility of life after death. It argues that the existence of a psychological duplicate is insufficient for resurrection, even if psychological continuity suffices for personal identity. That is because our persistence requires immanent causation. There are at most three ways of having life after death: if we are immaterial souls; if we are snatched bodily from our deathbeds; or if there is immanent causation ‘at a distance’ as Zimmerman proposes--but this requires an ontology of temporal (...) parts. (shrink)

"Jazz, the wound" : negative identity, culture, and the shadow of race -- America, or the stranger -- Negative identities of the subject in wartime America -- Critical theory goes to war : the critique of positive identity and positive science -- Negative modeling : objectivity, normativity, and the refusal of the universal -- Subject/object and disciplinarity.

I defend the Stoicizing view that Socrates in the Euthydemus really means what he says when he says that wisdom is the only good for a human being. By taking the deniers' case seriously and extending my Stoicizing interpretation to the Euthydemus as a whole, I aim to show how the dialogue calls into question three prominent assumptions that the deniers make, assumptions that reach far beyond the Euthydemus and that are made by more than just the deniers. First, the (...) deniers misread Socrates' argument that wisdom is the only good because they misunderstand what makes a protreptic argument successful. I show that the Euthydemus both raises a difficult question about reasons one might have for radical change in view and suggests a sophisticated answer. Second, the deniers' philosophical doubts about the Stoic claim rest on a mistaken interpretation of Socrates' ethical theory. I show that the Euthydemus offers a more plausible picture of Socratic eudaimonism that accommodates the Stoic claim. Third, when the deniers rely on evidence outside the Euthydemus to cast doubt on the Stoicizing reading, they rely on a dubious methodological assumption about how to read Plato's Socratic dialogues. I argue that the Euthydemus calls for a different approach. (shrink)

Carroll Izard completed his dissertation in 1952, beginning a career spanning more than six decades that coincided with clinical psychology maturing as a profession, and the birth of clinical science and cognitive neuroscience. Izard’s focus on discrete emotions as evolved systems that organize information, prepare responses, and shape the development of personality and relationships persisted through his career, despite “emotions” often being overshadowed by psychodynamic, behavioral, or cognitive perspectives. His theoretical work anticipated and now integrates contemporary neuroscience and relational perspectives. (...) Exploration of discrete emotions has kept lines of inquiry open that enrich our understanding of psychopathology. Izard also embraced clinical science, combining basic research with effectiveness studies addressing the unmet need for mental health services via emotion-focused interventions. (shrink)